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TNFSF18 抗体 (PE)

TNFSF18 适用: 小鼠 FACS, BR 宿主: 大鼠 Monoclonal YGL 386 PE
产品编号 ABIN2663705
发货至: 中国
  • 抗原 See all TNFSF18 抗体
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    适用
    • 61
    • 30
    • 6
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    • 1
    小鼠
    宿主
    • 52
    • 10
    • 6
    大鼠
    克隆类型
    • 51
    • 15
    • 1
    单克隆
    标记
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    • 1
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    This TNFSF18 antibody is conjugated to PE
    应用范围
    • 54
    • 32
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    • 8
    • 5
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    • 3
    • 2
    • 2
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    Flow Cytometry (FACS), Blocking Reagent (BR)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    YGL 386
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TNFSF18 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    别名
    GITR Ligand (TNFSF18 产品)
    别名
    Gitrl antibody, AITRL antibody, GITRL antibody, TL6 antibody, hGITRL antibody, TNLG2A antibody, tumor necrosis factor (ligand) superfamily, member 18 antibody, TNF superfamily member 18 antibody, Tnfsf18 antibody, TNFSF18 antibody
    背景
    GITR ligand (GITRL) is a member of the TNF superfamily, also known as TNFSF18 or TL6. It is expressed on B cells, macrophages, dendritic cells and endothelial cells. The expression of GITRL on dendritic cell surface can be transiently up-regulated and then rapidly down-regulated by LPS stimulation. GITRL binds to its receptor, GITR, to co-stimulate T cell activation, proliferation, and cytokine production, and inhibit the suppressive functions of CD4+CD25+ Treg cells, as well as induce macrophages activation. GITR-GITRL interaction has been implicated as an essential regulator of immune response to self antigens and phathogens.
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