FAS 抗体 (Pacific Blue)
Quick Overview for FAS 抗体 (Pacific Blue) (ABIN2662323)
抗原
See all FAS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Baboon, Capuchin Monkey, Chimpanzee, Marmoset, Saguinus oedipus, Cynomolgus, Pigtailed Macaque, 猕猴, Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)
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纯化方法
- The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from prolonged exposure to light. Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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别名
- CD95
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背景
- CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.
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途径
- p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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