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- 抗原 See all KLRA1 抗体
- KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This KLRA1 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
- 克隆位点
- YE1-48-10-6
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product KLRA1 Primary Antibody
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anti-Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1) (AA 66-171) antibody
KLRA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1) (C-Term) antibodyKLRA1 适用: 人, 小鼠, 大鼠 WB, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1) (Center) antibodyKLRA1 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))
- 别名
- Ly-49A (KLRA1 产品)
- 别名
- Klra2 antibody, Ly49i8 antibody, A1 antibody, Klra22 antibody, Ly49a antibody, Ly49o<129> antibody, Ly49v antibody, LY49 antibody, KLRA1 antibody, Ly49 antibody, killer cell lectin-like receptor, subfamily A, member 1 antibody, killer cell lectin-like receptor subfamily A, member 1 antibody, Klra1 antibody, KLRA1 antibody, LY49 antibody
- 背景
- Ly-49A is a 44 kD member of the C-type lectin/Ly-49 family proteins. It is a type-II transmembrane, disulfide-linked homodimer with C-type lectin extracellular domains. Ly-49A is present on a subset of NK and NK-T cells. Ly-49A, like other members of this family, inhibits NK cell activation through the recognition and interaction of certain MHC class I haplotypes on potential target cells. The Ly-49A receptor recognizes H-2Dd and H-2Dk, triggering phosphorylation of the ITIM motif in the cytoplasmic domain and recruitment of SHP-1 and SHP-2. The YE1/48.10.6 antibody reacts with NK cells from all mouse strains tested and reverses the inhibition of NK cytotoxicity.
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