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FAS 抗体 (FITC)

FAS 适用: 人 FACS 宿主: 小鼠 Monoclonal DX2 FITC
产品编号 ABIN2661868
发货至: 中国
  • 抗原 See all FAS 抗体
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This FAS antibody is conjugated to FITC
    应用范围
    • 157
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    Flow Cytometry (FACS)
    交叉反应
    Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Baboon, Capuchin Monkey, Chimpanzee, Marmoset, Saguinus oedipus, Cynomolgus, Pigtailed Macaque, 猕猴, Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    克隆位点
    DX2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product FAS Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    别名
    CD95 (FAS 产品)
    背景
    CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.
    途径
    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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