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CD8 alpha 抗体 (APC-Cy7)

CD8A 适用: 人 WB, IP, ICFC 宿主: 小鼠 Monoclonal RPA-T8 APC-Cy7
产品编号 ABIN2660733
发货至: 中国
  • 抗原 See all CD8 alpha (CD8A) 抗体
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD8 alpha antibody is conjugated to APC-Cy7
    应用范围
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    Western Blotting (WB), Immunoprecipitation (IP), Intracellular Flow Cytometry (ICFC)
    交叉反应
    Chimpanzee, Baboon, Cynomolgus, 猕猴, Pigtailed Macaque, Sooty mangabey (Cercocebus atys)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with APC/Cy7 under optimal conditions. The solution is free of unconjugated APC/Cy7 and unconjugated antibody.
    克隆位点
    RPA-T8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD8A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    别名
    CD8a (CD8A 产品)
    别名
    cd8 antibody, LOC100136450 antibody, BB154331 antibody, Ly-2 antibody, Ly-35 antibody, Ly-B antibody, Lyt-2 antibody, zgc:136643 antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, RHACD8-4 antibody, CD8a molecule antibody, uncharacterized LOC100125537 antibody, CD8 alpha antibody, CD8 antigen, alpha chain antibody, T-cell surface glycoprotein CD8 alpha chain antibody, Cd8a antibody, LOC100125537 antibody, LOC100136450 antibody, CD8A antibody, cd8a antibody, LOC100126556 antibody
    背景
    CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation, and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
    途径
    TCR Signaling
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