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- 抗原 See all CD103 (ITGAE) 抗体
- CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD103 antibody is conjugated to PE-Cy7
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC)
- 交叉反应
- Cynomolgus
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
- 克隆位点
- Ber-ACT8
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product ITGAE Primary Antibody
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anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) antibody
ITGAE 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGAE-2063 unconjugated
anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) antibodyITGAE 适用: 人 IHC, StM, ISt 宿主: 小鼠 Monoclonal ITGAE-2474 unconjugated
anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) antibodyITGAE 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) antibodyITGAE 适用: 人, Non-Human Primate FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal Ber-ACT8 unconjugated
anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) antibody (APC)ITGAE 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal Ber-ACT8 APC
anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) (AA 671-917) antibodyITGAE 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) (AA 19-200) antibodyITGAE 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) antibodyITGAE 适用: 小鼠 FACS, IHC, IP, IHC (fro) 宿主: 仓鼠 Monoclonal 2E7 unconjugated
anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) (AA 57-171) antibodyITGAE 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B8 unconjugated
anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) antibody (FITC)ITGAE 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal Ber-ACT8 FITC
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
- 别名
- CD103 (ITGAE 产品)
- 别名
- A530055J10 antibody, CD103 antibody, aM290 antibody, alpha-E1 antibody, alpha-M290 antibody, HUMINAE antibody, integrin alpha E, epithelial-associated antibody, integrin subunit alpha E antibody, Itgae antibody, ITGAE antibody
- 背景
- CD103 is a type I transmembrane glycoprotein also known as αE integrin, integrin αIEL chain, and human mucosal lymphocyte antigen 1. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. Treg cells express high level of CD103. Hairy cell leukemia has also been shown to express CD103. The expression of CD103 on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as an αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.
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