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- 抗原 See all TLR3 抗体
- TLR3 (Toll-Like Receptor 3 (TLR3))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This TLR3 antibody is conjugated to APC
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
- 克隆位点
- 11F8
- 亚型
- IgG2a
- Top Product
- Discover our top product TLR3 Primary Antibody
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anti-Toll-Like Receptor 3 (TLR3) (AA 404-532) antibody
TLR3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 464-647) antibodyTLR3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 801-905) antibodyTLR3 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 24-217) antibodyTLR3 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6F3G4 unconjugated
anti-Toll-Like Receptor 3 (TLR3) (C-Term) antibodyTLR3 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 135-297) antibodyTLR3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 55-70) antibodyTLR3 适用: 人, 猴, 山羊, 绵羊 WB, IHC, FACS, IP, IHC (p) 宿主: 小鼠 Monoclonal 40C1285-6 unconjugated
anti-Toll-Like Receptor 3 (TLR3) antibodyTLR3 适用: 小鼠 FACS, IF 宿主: 大鼠 Monoclonal 11F8 unconjugated
anti-Toll-Like Receptor 3 (TLR3) (C-Term) antibodyTLR3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 750-800), (pTyr759) antibodyTLR3 适用: 人 WB, IHC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.2 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- TLR3 (Toll-Like Receptor 3 (TLR3))
- 别名
- CD283 (TLR3 产品)
- 背景
- Toll-like receptor 3 (TLR3), also known as CD283, is type I transmembrane protein that belongs to the TLR family. It forms a large horseshoe shape that contacts a neighboring horseshoe, forming a dimer of two horseshoes. It is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. TLR3 is expressed selectively on the cytoplasmic membrane and intracellularly in dendritic cells. It is also highly expressed in the placenta, pancreas, heart, liver, lung, and muscle. TLR3 is a pattern recognition receptor that participates in innate immune response to microbial pathogens by recognizing polyinosine-polycytidylic acid (Poly(I:C)) and dsRNA. Ligand binding by TLR3 induces receptor dimerization which results in inducing NF-κB activation (via TRIF-linked RIP1/TLR3 interactions) and cytokine production. TLR3 has been shown to interact with a number of proteins including MYD88, TRAF6, TRIAD3, MAP3K7, and TAB2.
- 途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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