GATA3 抗体 (Alexa Fluor 488)
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- 抗原 See all GATA3 抗体
- GATA3 (GATA Binding Protein 3 (GATA3))
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GATA3 antibody is conjugated to Alexa Fluor 488
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
- 克隆位点
- 16E10A23
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product GATA3 Primary Antibody
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anti-GATA Binding Protein 3 (GATA3) antibody
GATA3 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1A10A11 unconjugated
anti-GATA Binding Protein 3 (GATA3) (N-Term) antibodyGATA3 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 斑马鱼, 兔, 马, 豚鼠, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 1-260) antibodyGATA3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 103-200) antibodyGATA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 103-200) antibodyGATA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A4 unconjugated
anti-GATA Binding Protein 3 (GATA3) (pSer308) antibodyGATA3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 1-444) antibodyGATA3 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 1259CT707-136-102 unconjugated
anti-GATA Binding Protein 3 (GATA3) (C-Term) antibodyGATA3 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠, 绵羊 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 36-85) antibodyGATA3 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 斑马鱼, 兔, 马, 小鸡, 绵羊, 猴, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 357-436) antibodyGATA3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GATA3-2442 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C
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- 抗原
- GATA3 (GATA Binding Protein 3 (GATA3))
- 别名
- GATA3 (GATA3 产品)
- 别名
- HDR antibody, HDRS antibody, Gata-3 antibody, jal antibody, cb550 antibody, gta3 antibody, GATA-3 antibody, XGATA3 antibody, xgata-3 antibody, hdr antibody, xGATA-3 antibody, GATA3 antibody, GATA transcription factor 3 antibody, T4L20.260 antibody, T4L20_260 antibody, gata3 antibody, ZH-DR antibody, zgc:103531 antibody, GATA binding protein 3 antibody, GATA binding protein 3 S homeolog antibody, GATA transcription factor 3 antibody, amidase antibody, putative amidase antibody, GATA-binding protein 3 antibody, hematopoietic death receptor antibody, GATA3 antibody, Gata3 antibody, gata3 antibody, gata3.S antibody, gatA3 antibody, hdr antibody
- 背景
- GATA3 functions as a major regulator of T helper 2 (Th2) cell differentiation in immune cells. GATA3 expression is upregulated through IL-4 receptor signaling or the Notch-mediated pathway, which results in production of IL-4, IL-5, and IL-13 cytokines, responsible for preferential differentiation of Th2-cells. GATA3 has been shown to regulate early developmental processes of T cells, such as T cell commitment, positive selection, and post-commitment CD4+ T cell survival. In the mammary gland, GATA3 plays an important role in differentiation and commitment of luminal epithelial cells. In a mouse model, exogenous expression of GATA3 in undifferentiated breast carcinoma cells induces differentiation and suppresses spreading of the tumor cells, suggesting that GATA3 is involved in preventing malignancy of breast cancer. GATA3 has been reported to be essential in the development of a variety of normal tissues. Defect in GATA3 results in hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR syndrome).
- 途径
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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