COPS3 抗体
-
- 抗原 See all COPS3 抗体
- COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This COPS3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of JAB1/COPS3 protein. (region surrounding Met408)
- 交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product COPS3 Primary Antibody
-
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 324-422) antibody
COPS3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D10 unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 324-422) antibodyCOPS3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 194-423) antibodyCOPS3 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 324-422) antibodyCOPS3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D10 unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (C-Term) antibodyCOPS3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) antibodyCOPS3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 139-390) antibodyCOPS3 适用: 人, 大鼠 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) antibodyCOPS3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) antibodyCOPS3 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 194-423) antibodyCOPS3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
-
- 抗原
- COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))
- 别名
- COPS3 (COPS3 产品)
- 别名
- CG18332 antibody, CH3 antibody, Csn3 antibody, DCH3 antibody, Dch3 antibody, Dmel\\CG18332 antibody, FBgn0027055 antibody, dCSN3 antibody, COPS3 antibody, CSN3 antibody, DKFZp468P1922 antibody, Sgn3 antibody, wu:fc32a02 antibody, wu:fk59f01 antibody, zgc:111903 antibody, zgc:55643 antibody, zgc:77615 antibody, CONSTITUTIVE PHOTOMORPHOGENIC 13 antibody, COP9 SIGNALOSOME SUBUNIT 3 antibody, F18O22.40 antibody, F18O22_40 antibody, FUS11 antibody, FUSCA 11 antibody, SGN3 antibody, csn3 antibody, COP9 signalosome subunit 3 antibody, Proteasome component (PCI) domain protein antibody, COP9 signalosome subunit 3 L homeolog antibody, COP9 signalosome complex subunit 3 antibody, CSN3 antibody, cops3 antibody, COPS3 antibody, Cops3 antibody, COP13 antibody, cops3.L antibody, csn-3 antibody
- 背景
- Genes belonging to the Jun and Fos oncogene families encode nuclear proteins that are found to be associated with a number of transcriptional complexes. The c-Jun protein is a major component of the transcription factor AP-1, originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA-response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, but the Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. The coactivator of Jun, designated JAB1 (for Junactivation domain-binding protein), interacts with c-Jun and Jun D, but not with Jun B or v-Jun. This interaction enhances the transactivating ability of Jun proteins by stabilizing their binding to the TRE.Synonyms: COP9 signalosome complex subunit 3, CSN3, JAB1-containing signalosome subunit 3, SGN3, Signalosome subunit 3
- 分子量
- approx. 47 kDa
- 基因ID
- 8533
- NCBI登录号
- NP_001186054
- UniProt
- Q9UNS2
- 途径
- Cell Division Cycle
-
