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GLUT1 抗体

SLC2A1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265442
发货至: 中国
  • 抗原 See all GLUT1 (SLC2A1) 抗体
    GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 68
    • 11
    • 5
    克隆类型
    • 57
    • 27
    多克隆
    标记
    • 55
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    This GLUT1 antibody is un-conjugated
    应用范围
    • 56
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of GLUT1 protein.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product SLC2A1 Primary Antibody
  • 应用备注
    ELISA: 1/5000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))
    别名
    GLUT1 / SLC2A1 (SLC2A1 产品)
    别名
    DYT17 antibody, DYT18 antibody, DYT9 antibody, EIG12 antibody, GLUT antibody, GLUT1 antibody, GLUT1DS antibody, HTLVR antibody, PED antibody, Glut-1 antibody, Glut1 antibody, GLUTB antibody, GTG1 antibody, Gtg3 antibody, RATGTG1 antibody, SLC2A1 antibody, GLT1 antibody, GLUCOSE TRANSPORTER 1 antibody, T21H19.70 antibody, T21H19_70 antibody, plastidic GLC translocator antibody, glut1 antibody, ped antibody, slc2a1 antibody, slc2a14 antibody, solute carrier family 2 member 1 antibody, solute carrier family 2 (facilitated glucose transporter), member 1 antibody, plastidic GLC translocator antibody, solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog antibody, SLC2A1 antibody, Slc2a1 antibody, PGLCT antibody, slc2a1.L antibody
    背景
    Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the redistribution of the insulin-inducible glucose transporter, Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane, and shows a much less dramatic translocation in response to insulin. Glut1 and Glut4 are twelve pass transmembrane proteins (12TM) whose carboxytermini may dictate their cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity.Synonyms: GLUT-1, Glucose Transporter 1, Glucose transporter type 1, Glucose transporter type 1 erythrocyte/brain, HepG2 glucose transporter, Solute carrier family 2 facilitated glucose transporter member 1
    分子量
    approx. 55 kDa
    基因ID
    6513
    NCBI登录号
    NP_006507
    UniProt
    P11166
    途径
    Sensory Perception of Sound, Dicarboxylic Acid Transport, Warburg Effect
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