GFRA1 抗体
-
- 抗原 See all GFRA1 抗体
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This GFRA1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of GFR alpha-1 protein. (region surrounding Lys90)
- 交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product GFRA1 Primary Antibody
-
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 239-350) antibody
GFRA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 25-280) antibodyGFRA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 351-429) antibodyGFRA1 适用: 人, 小鼠, 山羊 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 230-385) antibodyGFRA1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 32-119) antibodyGFRA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 32-119) antibodyGFRA1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4D8 unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 369-382) antibodyGFRA1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) antibodyGFRA1 适用: 人 WB, ELISA, IF 宿主: 小鸡 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 25-227) antibodyGFRA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 72-83), (Extracellular Domain) antibodyGFRA1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, LCI 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA: 1: 1000approx. 1: 20000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
- 别名
- GFRA1 / GDNFR-alpha (GFRA1 产品)
- 别名
- gdnfr antibody, ret1l antibody, retl1 antibody, trnr1 antibody, gdnfra antibody, MGC122616 antibody, gfr-alpha-1 antibody, GDNFR antibody, GDNFRA antibody, GFR-ALPHA-1 antibody, RET1L antibody, RETL1 antibody, TRNR1 antibody, GDNFRALPHA antibody, GFRA1 antibody, AU042498 antibody, gfralpha1a antibody, zgc:110129 antibody, GDNF family receptor alpha 1 antibody, glial cell line derived neurotrophic factor family receptor alpha 1 antibody, gdnf family receptor alpha 1a antibody, gfra1 antibody, GFRA1 antibody, Gfra1 antibody, gfra1a antibody
- 背景
- Glial cell line-derived neurotrophic factor (GDNF) and the related neurotrophic factor neurturin (NTN) are potent survival factors for central and peripheral neurons. GDNF is a glycosylated, disulfide-bonded homodimer that is distantly related to the TGFβ superfamily of growth factors. Three receptors for these factors, GFRα-1 (also designated GDNFR-α, RETL1 or TrnR-1), GFRα-2 (also designated GDNFR-β, RETL2, NTNR-α or TrnR-2) and GFRα-3 have been identified. The receptors do not contain transmembrane domains and are attached to the cell membrane by glycosyl-phosphoinositol linkage. Both GFRα-1 and GFRα-2 have been shown to mediate the GDNF-dependent and NTN-dependent phosphorylation and activation of the tyrosine kinase Ret. GFRα-3 is expressed only during development.Synonyms: GDNF family receptor alpha-1, GDNF receptor alpha, GDNFRA, GFR-alpha-1, RET ligand 1, RETL1, TGF-beta-related neurotrophic factor receptor 1, TRNR1
- 分子量
- approx. 51 kDa
- 基因ID
- 2674
- NCBI登录号
- NP_005255
- UniProt
- P56159
-
