(1 reference)-
- 抗原 See all Fibrillin 1 (FBN1) 抗体
- Fibrillin 1 (FBN1)
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Fibrillin 1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Fibrillin-1 protein. (region surrounding asn2843)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product FBN1 Primary Antibody
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anti-Fibrillin 1 (FBN1) (AA 246-389) antibody
FBN1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibrillin 1 (FBN1) (AA 751-895) antibodyFBN1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibrillin 1 (FBN1) (Internal Region) antibodyVerified FBN1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Fibrillin 1 (FBN1) (AA 723-902) antibodyFBN1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibrillin 1 (FBN1) (AA 1703-1889) antibodyFBN1 适用: 小鼠 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibrillin 1 (FBN1) (AA 360-460) antibodyFBN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibrillin 1 (FBN1) (AA 959-1145) antibodyFBN1 适用: 小鼠 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibrillin 1 (FBN1) (AA 168-364) antibodyFBN1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibrillin 1 (FBN1) (AA 401-500) antibodyFBN1 适用: 人, 大鼠 ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Fibrillin 1 (FBN1) (AA 2772-2871) antibodyFBN1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H6 unconjugated
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- 应用备注
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ELISA: 1/40000-1/60000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "A potential new role for myofibroblasts in remodeling of sub-rupture fatigue tendon injuries by exercise." in: Scientific reports, Vol. 8, Issue 1, pp. 8933, (2018) (PubMed).
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: "A potential new role for myofibroblasts in remodeling of sub-rupture fatigue tendon injuries by exercise." in: Scientific reports, Vol. 8, Issue 1, pp. 8933, (2018) (PubMed).
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- 抗原
- Fibrillin 1 (FBN1)
- 别名
- Fibrillin-1 (FBN1 产品)
- 别名
- FBN1 antibody, ACMICD antibody, ECTOL1 antibody, FBN antibody, GPHYSD2 antibody, MASS antibody, MFS1 antibody, OCTD antibody, SGS antibody, SSKS antibody, WMS antibody, WMS2 antibody, AI536462 antibody, B430209H23 antibody, Fib-1 antibody, Tsk antibody, fibrillin 1 antibody, FBN1 antibody, Fbn1 antibody
- 背景
- The fibrillin family of proteins, including fibrillin-1 (FBN1) and fibrillin-2 (FBN2), are integral components of a distinct subset of extracellular microfibrils. Microfibrils are found in elastic tissues where they facilitate elastic fiber formation and in nonelastic tissue where they support the association of the epithelial cells with the interstitial matrix. Characteristic of the fibrillin proteins are the epidermal growth factor (EGF)-like motifs, which contain a consensus sequence for calcium binding. This calcium association may be critical for protein-protein interactions and stabilization of the microfibrils. Mutations of the FBN1 gene have been shown to result in Marfan syndrome, a disease characterized by abnormal synthesis, secretion and matrix deposition of fibrillin. FBN2 is also linked to a rare, yet similiar, skeletal disorder, congenital contractural arachnodactyly.Synonyms: FBN, FBN1
- 基因ID
- 2200
- NCBI登录号
- NP_000129
- UniProt
- P35555
- 途径
- Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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