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Cytochrome C 抗体

The 兔 多克隆 anti-Cytochrome C antibody (ABIN265383) specifically detects Cytochrome C in WB 和 IHC (p). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN265383
发货至: 中国
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Quick Overview for Cytochrome C 抗体 (ABIN265383)

抗原

See all Cytochrome C (CYCS) 抗体
Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Cytochrome C antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of Cytochrome c protein (region surrounding His19).

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography using epitope-specific immunogen
  • 应用备注

    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C or (in aliquotes) at -20 °C for longer.
  • 抗原

    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

    别名

    Cytochrome C

    背景

    Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in the process of oxidative phosphorylation and production of cellular ATP. An increasing amount of interest has been directed toward the role which cytocrome C has been demonstrated to play in apoptotic processes. Following exposure to apoptotic stimuli, cytochrome C is rapidly released from the mitochondria into the cytosol, an event which may be required for the completion of apoptosis in some systems. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.Synonyms: CYC, CYCS

    分子量

    approx. 15,35 kDa

    基因ID

    54205

    NCBI登录号

    NP_061820

    UniProt

    P99999

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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