Connexin 43/GJA1 抗体
Quick Overview for Connexin 43/GJA1 抗体 (ABIN265368)
抗原
See all Connexin 43/GJA1 (GJA1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of GJA1 / Cx43 protein(region surrounding Ser369).
-
交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen.
-
-
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibody
GJA1 适用: 人, 大鼠, 小鼠, 犬, Cow, 猴, 兔, 小鸡, 豚鼠, Pig, 马, 绵羊, Hamster, 山羊, 驴, Avian, Cat WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (pSer368) antibodyGJA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 107-138) antibodyGJA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 351-367) antibodyGJA1 适用: 人, 大鼠, 小鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 211-260) antibodyGJA1 适用: 人, 大鼠, 小鼠, 犬 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 244-382) antibodyGJA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 233-382) antibodyGJA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibodyGJA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 233-382) antibodyGJA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (N-Term) antibodyGJA1 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, 豚鼠, 斑马鱼, 马, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid Repeated freeze/thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
-
别名
- GJA1 / Cx43
-
背景
- Connexin 43 (Cx43) is a member of the large family of gap junction proteins. Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels. Clusters of these channels assemble to make gap junctions. Gap junction communication is important in development and regulation of cell growth. Phosphorylation of Cx43 is important in regulating assembly and function of gap junctions. Ser368 of Cx43 is phosphorylated by protein kinase C (PKC) after activation by phorbol esters, which decreases cell-to-cell communication. Src can interact with and phosphorylate Cx43 to alter gap junction communication.Synonyms: Connexin-43, GJAL, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein
-
分子量
- approx. 43 kDa
-
基因ID
- 2697
-
NCBI登录号
- NP_000156
-
UniProt
- P17302
-
途径
- MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
抗原
-
