BAK1 抗体
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北京 101111
Quick Overview for BAK1 抗体 (ABIN265324)
抗原
See all BAK1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Bak1/2 protein. (region surrounding Ala2)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % pure SDS-PAGE
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anti-BCL2-Antagonist/killer 1 (BAK1) (AA 62-112) antibody
BAK1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Antagonist/killer 1 (BAK1) (AA 29-187) antibodyBAK1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2H9H7 unconjugated
anti-BCL2-Antagonist/killer 1 (BAK1) (AA 22-211) antibodyBAK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Antagonist/killer 1 (BAK1) antibodyBAK1 适用: 人 WB, IHC, ELISA, FACS, IP 宿主: 兔 Monoclonal 8D1 unconjugated Recombinant Antibody
anti-BCL2-Antagonist/killer 1 (BAK1) (AA 21-120) antibodyBAK1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Antagonist/killer 1 (BAK1) (AA 1-14) antibodyBAK1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Antagonist/killer 1 (BAK1) antibodyBAK1 适用: 人, Hamster, 猴, Pig WB, IHC, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Antagonist/killer 1 (BAK1) (N-Term) antibodyBAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Antagonist/killer 1 (BAK1) (N-Term) antibodyBAK1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Antagonist/killer 1 (BAK1) (AA 1-211) antibodyBAK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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别名
- Bcl-2-Like 7
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背景
- Bak or Bcl2 homologous antagonist is a member of the Bcl2 family of proteins. The Bcl-2 related proteins interact with one another through the formation of homo and heterodimers. The susceptibility of cells to apoptotic stimuli is thought to be controlled by the relative ratios of the different Bcl2 family proteins. Bak has been demonstrated to accelerate the rate of apoptosis in growth factor deprived murine lymphoid, neuronal and fibroblastic cell lines. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. Bak also interacts with the tumor suppressor P53 after exposure to cell stress.Synonyms: Apoptosis regulator BAK, BAK, BAK1, BCL2L7, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, Bcl2-L-7, CDN1, cell death inhibitor 1
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分子量
- approx. 25 kDa
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基因ID
- 578
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NCBI登录号
- NP_001179
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UniProt
- Q16611
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途径
- Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
抗原
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