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Netrin 1 抗体

NTN1 适用: 人, 小鼠, 大鼠, 猴, Cow, Cat WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265184
发货至: 中国
  • 抗原 See all Netrin 1 (NTN1) 抗体
    Netrin 1 (NTN1)
    适用
    • 47
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    • 3
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    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 猴, Cow, Cat
    宿主
    • 55
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    克隆类型
    • 61
    • 8
    多克隆
    标记
    • 38
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Netrin 1 antibody is un-conjugated
    应用范围
    • 52
    • 22
    • 20
    • 13
    • 13
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects NTN1. Tested on MDCKII cell lysates.
    纯化方法
    Purified
    免疫原
    Synthetic peptide derived from the human Netrin 1 protein
    亚型
    IgG
    Top Product
    Discover our top product NTN1 Primary Antibody
  • 应用备注
    Western blot (0.5-2 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
  • 抗原
    Netrin 1 (NTN1)
    别名
    Netrin-1 (NTN1 产品)
    别名
    ntn1-A antibody, Netrin-1 antibody, NTN1 antibody, unc-6 antibody, MGC147073 antibody, NTN1L antibody, AI561871 antibody, BC019633 antibody, netrin-1 antibody, netrin 1 L homeolog antibody, netrin 1 antibody, ntn1.L antibody, NTN1 antibody, ntn1 antibody, Ntn1 antibody
    背景
    Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis. Netrin 1's main receptor is DCC (deleted in colorectal cancer- a putative tumor suppressor gene whose expression is lost in numerous cancers). DCC belongs to the so-called family of dependence receptors. These receptors induce apoptosis when their ligand is absent, thus conferring a state of cellular dependence on Netrin 1 availability. The DCC/netrin-1 duo regulates neuron survival during nervous system development. The mechanism(s) by which Netrin 1/ DCC triggers cell death are still unknown. The localization of DCC to lipid rafts appears to be a prerequisite for its proapoptotic activity.Synonyms: NTN1, NTN1L
    基因ID
    9423
    NCBI登录号
    NP_004813
    UniProt
    O95631
    途径
    Regulation of Cell Size
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