PPAPDC2 抗体
-
- 抗原 See all PPAPDC2 抗体
- PPAPDC2 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PPAPDC2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 特异性
- This antibody reacts to Phosphatidic Acid Phosphatase Domain Containing 2 (PPAPDC2).
- 纯化方法
- Affinity Purified
- 免疫原
- Synthetic peptide derived from human phosphatidic acid phosphatase type 2 domain containing 2 (PPAPDC2)
- Top Product
- Discover our top product PPAPDC2 Primary Antibody
-
anti-Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2) antibody
PPAPDC2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2) (C-Term) antibodyPPAPDC2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2) (AA 71-120) antibodyPPAPDC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2) (N-Term) antibodyPPAPDC2 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Western Blot: 1: 400 - 1: 800. Positive Control: Testis.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Ship on gel ice. Store (in aliquots) at -20 °C only.
-
- 抗原
- PPAPDC2 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2))
- 别名
- PPAPDC2 (PPAPDC2 产品)
- 别名
- PPAPDC2 antibody, PDP1 antibody, PSDP antibody, bA6J24.6 antibody, 4932443D16Rik antibody, phospholipid phosphatase 6 antibody, PLPP6 antibody, plpp6 antibody, Plpp6 antibody
- 背景
- Upon cell activation Presqualene diphosphate (PSDP)2, a bioactive lipid, rapidly remodels to presqualene monophosphate (PSMP). A newly identified and characterized phosphatase (phosphatidic acid phosphatase domain containing 2 (PPAPDC2)) has recent,y been shown to convert PSDP to PSMP. Unlike the related polyisoprenyl phosphate farnesyl diphosphate (FDP), PSDP has been shown not to be a substrate for type 2 lipid phosphate phosphohydrolases. PSDP phosphatase activity has been identified in activated human neutrophil (PMN) extracts. Recombinant PPAPDC2 displays diphosphate phosphatase activity with substrate preference for PSDP > FDP phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and optimal at pH 7.0 - 8.0. PPAPDC2 mRNA has been detected in human PMN, and is widely expressed in human tissues. PPAPDC2 expressed in human PMN is first lipid phosphate phosphohydrolase identified for PSDP. The regulation of this enzymes activity has important implications for PMN activation in innate immunity.Synonyms: PPAP2 domain-containing protein 2, Phosphatidic acid phosphatase type 2 domain-containing protein 2, Presqualene diphosphate phosphatase
- 基因ID
- 403313
- NCBI登录号
- NP_982278
- UniProt
- Q8IY26
-
