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SLA 抗体

SLA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265047
发货至: 中国
  • 抗原 See all SLA 抗体
    SLA (Src-Like-Adaptor (SLA))
    适用
    • 16
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 12
    • 4
    克隆类型
    • 14
    • 2
    多克隆
    标记
    • 12
    • 2
    • 1
    • 1
    This SLA antibody is un-conjugated
    应用范围
    • 12
    • 9
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB)
    特异性
    This antibody reacts to SLA.
    纯化方法
    Purified
    免疫原
    Synthetic peptide derived from the human SLAP1 protein.
    亚型
    IgG
    Top Product
    Discover our top product SLA Primary Antibody
  • 应用备注
    Western Blot: 5 - 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原
    SLA (Src-Like-Adaptor (SLA))
    别名
    SLA (SLA 产品)
    别名
    SLA1 antibody, SLAP antibody, src-like-adapter antibody, SLA antibody, Slap1 antibody, Slap antibody, Slap-1 antibody, Src like adaptor antibody, Src-like-adaptor antibody, src-like adaptor antibody, SLA antibody, Sla antibody
    背景
    Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. Interacts with EPHA2, VAV1, LCP2 and PDGFRB. The C-terminal domain is essential for the homodimerization and the interaction with CBL. While the interaction with CBL is apparently mediated via the hydrophobic region of this domain, the highly charged region is apparently required for the homodimerization. Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas.Synonyms: SLAP, SLAP-1, SLAP1, Src-like-adapter, Src-like-adapter protein 1
    基因ID
    6503
    NCBI登录号
    NP_001039021
    UniProt
    Q13239
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