PPAP2C 抗体
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- 抗原 See all PPAP2C 抗体
- PPAP2C (Phosphatidic Acid Phosphatase Type 2C (PPAP2C))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPAP2C antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody reacts to Lyosphospholipid Phosphatase (LPP) 2.
- 纯化方法
- Purified
- 免疫原
- Unique peptide derived from the human lysophospholipid phosphatase 2 protein.
- 亚型
- IgG
- Top Product
- Discover our top product PPAP2C Primary Antibody
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anti-Phosphatidic Acid Phosphatase Type 2C (PPAP2C) (AA 109-162) antibody
PPAP2C 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2C (PPAP2C) antibodyPPAP2C 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2C (PPAP2C) (AA 227-254), (C-Term) antibodyPPAP2C 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB17209 unconjugated
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- 应用备注
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Western Blot: 10 - 15 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- 抗原
- PPAP2C (Phosphatidic Acid Phosphatase Type 2C (PPAP2C))
- 别名
- PPAP2C / LPP2 (PPAP2C 产品)
- 别名
- fj16e10 antibody, wu:fj16e10 antibody, zgc:66434 antibody, ppap2c antibody, MGC75849 antibody, MGC81169 antibody, LPP2 antibody, PAP-2c antibody, PAP2-g antibody, Lpp2 antibody, phospholipid phosphatase 2b antibody, phospholipid phosphatase 2 antibody, phospholipid phosphatase 2 S homeolog antibody, phosphatidic acid phosphatase type 2C antibody, plpp2b antibody, plpp2 antibody, plpp2.S antibody, PLPP2 antibody, Plpp2 antibody, PPAP2C antibody
- 背景
- Phosphatidic acid phosphatase type 2 (PAP2) was originally identified as a plasma membrane enzyme that catalyses the dephosphorylation of the putative second messenger, phosphatidic acid (PA) to diacylglycerol (DG) [1]. Subsequently, multiple isoforms of PAP2 were cloned [2-5]. It was found that these enzymes dephosphorylate a number of lipid phosphates in vitro other than PA, including the potent bioactive lipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Therefore, they have been renamed lipid phosphate phosphatases (LPPs). Currently, there are four members of this family called LPP1, LPP1a, LPP2 and LPP3 [6]. S1P [7] and LPA [8] regulate the proliferation, differentiation, apoptosis and migration of cells by binding to a family of G protein-coupled receptors. Thus, EDG1/S1P1, EDG3/S1P3, EDG5/S1P2/AGR16/H218, EDG6/S1P4 and EDG8/S1P5/nrg-1 are high affinity S1P receptors [7] whereas EDG2/LPA1, EDG4/LPA2 and EDG7/LPA3 have high affinity for LPA [8]. Recently, the over-expression of LPP1 was shown to limit LPA-stimulated signalling in Rat2 fibroblasts [9] and LPA-stimulated DNA synthesis in HEK 293 cells [10]. Similarly, over-expression of LPP1, LPP1a and LPP2 attenuate S1P-signalling to the p42/p44 mitogen activated protein kinase cascade [11].Synonyms: Lipid phosphate phosphohydrolase 2, PAP2-gamma, Phosphatidate phosphohydrolase type 2c, Phosphatidic acid phosphatase 2c
- 基因ID
- 8612
- NCBI登录号
- NP_003703
- UniProt
- O43688
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