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ADAM10 抗体 (AA 732-748)

ADAM10 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN264988
发货至: 中国
  • 抗原 See all ADAM10 抗体
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    抗原表位
    • 15
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 732-748
    适用
    • 66
    • 32
    • 32
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 53
    • 13
    • 2
    • 1
    克隆类型
    • 46
    • 23
    多克隆
    标记
    • 36
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM10 antibody is un-conjugated
    应用范围
    • 48
    • 17
    • 16
    • 15
    • 13
    • 13
    • 8
    • 8
    • 7
    • 7
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody recognizes ADAM10.
    纯化方法
    Purified
    免疫原
    Synthetic peptide corresponding to amino acids 732-748 off the Human ADAM10.
    亚型
    IgG
    Top Product
    Discover our top product ADAM10 Primary Antibody
  • 应用备注
    Western Blot: 0.25-1 μg/mL. Detects an 85 kDa band can be detected in Jurkat cell lysates which may representprecursor protein. A faint 60 kDa band is also detected in some cell lines, including Jurkat,which may be processed mature protein. Positive Control/Tissue Expression: Jurkat whole cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate buffered saline solution containing 0.02 % Sodium Azide as a preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C.
  • 抗原
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    别名
    CD156c / ADAM10 (ADAM10 产品)
    别名
    ADAM10 antibody, Adam10 antibody, adam10 antibody, wu:fc03d12 antibody, ad10 antibody, cd156c antibody, kuz antibody, kuzbanian antibody, madm antibody, xadam10 antibody, ADAM-10 antibody, ADAM 10 antibody, AD10 antibody, CD156c antibody, HsT18717 antibody, MADM antibody, 1700031C13Rik antibody, LOC100219653 antibody, zgc:64203 antibody, ADAM metallopeptidase domain 10 antibody, ADAM metallopeptidase domain 10a antibody, ADAM metallopeptidase domain 10 S homeolog antibody, a disintegrin and metallopeptidase domain 10 antibody, ADAM metallopeptidase domain 10b antibody, ADAM10 antibody, Adam10 antibody, adam10a antibody, adam10.S antibody, adam10b antibody
    背景
    Proinflammatory cytokine tumor necrosis factor-a (TNF-a) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta (1-3). The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively, (1,2,4). ADAM10 mRNA is expressed in a variety of human and bovine tissues (1,4).Synonyms: Disintegrin and metalloproteinase domain-containing protein 10, KUZ, Kuzbanian protein homolog, MADM, Mammalian disintegrin-metalloprotease
    基因ID
    102
    NCBI登录号
    NP_001101
    UniProt
    O14672
    途径
    Notch Signaling, EGFR Signaling Pathway
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