ATIC 抗体
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- 抗原 See all ATIC 抗体
- ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))
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适用
- 人, 小鼠, 大鼠, Drosophila melanogaster, Frog
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ATIC antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody detects Phosphoribosylaminoimidazolecarboxamide Formyltransferase (ATIC).
- 产品特性
- Synonyms: IMP cyclohydrolase, Inosinicase, IMP synthetase, Bifunctional purine biosynthesis proteinPURH
- 纯化方法
- Affinity chromatography.
- 免疫原
- Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the human ATIC protein and mouse myeloma Ag8563 cells. Sequence common in Frog, Fruit fly, Rat and Mouse.
- 克隆位点
- F38 P7 H9
- 亚型
- IgG1
- Top Product
- Discover our top product ATIC Primary Antibody
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anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (AA 301-592) antibody
ATIC 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (C-Term) antibodyATIC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) antibodyATIC 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, FACS 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) antibodyATIC 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) antibodyATIC 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) antibodyATIC 适用: 人, 犬, 兔, 马, Cow, Pig, Drosophila melanogaster, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal F38 P7 H9 unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (AA 1-592) antibodyATIC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (AA 1-592) antibodyATIC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (AA 379-428) antibodyATIC 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, Pig, 豚鼠, Hamster, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) antibodyATIC 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal F38 P7 H9 unconjugated
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- 应用备注
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Western Blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections (15 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1 x TBSwithTween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- Phosphate buffered saline with 0.08 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
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The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))
- 别名
- ATIC / PURH (ATIC 产品)
- 别名
- AICAR antibody, AICARFT antibody, IMPCHASE antibody, PURH antibody, purH antibody, 2610509C24Rik antibody, AA536954 antibody, AW212393 antibody, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase L homeolog antibody, bifunctional purine biosynthesis protein PurH antibody, bifunctional purine biosynthesis protein purH antibody, Bifunctional purine biosynthesis protein purH antibody, Bifunctional purine biosynthesis protein PurH antibody, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase antibody, atic.L antibody, purH antibody, ATIC antibody, Atic antibody
- 背景
- The bifunctional purine biosynthesis protein PURH contains phosphoribosylaminoimidazole carboxamide formyltransferase, also designated AICAR transformylase, IMP cyclohydrolase or Inosinicase. AICAR plays an important role in purine biosynthesis, specifically in the production of nucleotides and IMP. Defects in ATIC, the gene encoding for this protein, can cause AICArebosuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-ribotide, also designated ZMP, and its derivatives in erythrocytes and fibroblasts and also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.Synonyms: Bifunctional purine biosynthesis protein PURH, IMP cyclohydrolase, IMP synthetase, Inosinicase
- 基因ID
- 471
- UniProt
- P31939
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