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CYP2A6 抗体 (C-Term, pSer472)

CYP2A6 适用: 人 WB, IHC (fro), EIA 宿主: 小鼠 Monoclonal F16 P2 D8 unconjugated
产品编号 ABIN264498
发货至: 中国
  • 抗原 See all CYP2A6 抗体
    CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))
    抗原表位
    • 15
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term, pSer472
    适用
    • 42
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 37
    • 5
    小鼠
    克隆类型
    • 38
    • 4
    单克隆
    标记
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP2A6 antibody is un-conjugated
    应用范围
    • 37
    • 14
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to Cytochrome p450 2A6.
    产品特性
    Synonyms: CYP2A3, Cytochrome P450 2A6, CYPIIA6, CYPIIA3, Coumarin 7-hydroxylase
    纯化方法
    Purified
    免疫原
    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized withSynthetic peptide conjugated to ovalbumin derived from the C-terminus of CYP2A6 andmouse myeloma Ag8563 cells. Antigen identical in CYP2A6, 2A7 and 2A13.
    克隆位点
    F16 P2 D8
    亚型
    IgG1
    Top Product
    Discover our top product CYP2A6 Primary Antibody
  • 应用备注
    ELISA. Immunohistochemistry on paraffin sections. Western Blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))
    别名
    CYP2A6 (CYP2A6 产品)
    别名
    CPA6 antibody, CYP2A antibody, CYP2A3 antibody, CYPIIA6 antibody, P450C2A antibody, P450PB antibody, cyp2a6 antibody, cytochrome P450 family 2 subfamily A member 6 antibody, cytochrome P450 2A6 antibody, cytochrome P450 family 2 subfamily A member 6 L homeolog antibody, CYP2A6 antibody, cyp2a6.L antibody
    背景
    The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP2A6 is a liver enzyme that metabolizes a number of drugs and a variety of procarcinogens, though it is primarily responsible for the metabolism of nicotine, the major addictive agent in tobacco. CYP2A6 inactivates nicotine to cotinine, and then cotinine to 3-hydroxycotinine. Differences in CYP2A6 genotypes are related to nicotine dependence, and may influence smoking habits and withdrawal symptoms in individuals that are quitting smoking. This suggests that an individualized smoking cessation program may be designed based on CYP2A6 genotypes.Synonyms: CYP2A3, CYPIIA3, CYPIIA6, Coumarin 7-hydroxylase, Cytochrome P450 2A6
    基因ID
    1548
    UniProt
    P11509
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