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PTGER2 抗体

PTGER2 适用: 人, 大鼠, Cow WB 宿主: 小鼠 Monoclonal 3-00E-006 unconjugated
产品编号 ABIN264447
发货至: 中国
  • 抗原 See all PTGER2 抗体
    PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))
    适用
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    人, 大鼠, Cow
    宿主
    • 59
    • 7
    小鼠
    克隆类型
    • 59
    • 7
    单克隆
    标记
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    This PTGER2 antibody is un-conjugated
    应用范围
    • 51
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    Western Blotting (WB)
    特异性
    This antibody detects Prostaglandin E2 Receptor EP2 subtype.
    产品特性
    Synonyms: Prostaglandin E receptor 2, Prostanoid EP2 receptor, Prostaglandin E2 receptor EP2, PGEreceptor EP2, PGE2 receptor EP2 subtype, EP2
    纯化方法
    Protein A/G Chromatography
    免疫原
    Hybridoma produced by the fusion of splenocytes from mice immunized with recombinanthuman EP2 receptor protein and mouse myeloma cells.
    克隆位点
    3-00E-006
    亚型
    IgG1
    Top Product
    Discover our top product PTGER2 Primary Antibody
  • 应用备注
    Western Blot: 1-5 μg/mL. Positive Control: Porcine brain lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.08 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C. Can be shipped at 2-8 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))
    别名
    PTGER2 (PTGER2 产品)
    别名
    EP2 antibody, Ptgerep2 antibody, ptger2 antibody, ptger2l antibody, zgc:63974 antibody, MGC69060 antibody, PTGER2 antibody, Ptger-ep2 antibody, si:ch211-13n20.1 antibody, si:dkey-29m11.3 antibody, zgc:136608 antibody, prostaglandin E receptor 2 antibody, prostaglandin E receptor 2 (subtype EP2) antibody, prostaglandin E receptor 2a (subtype EP2) antibody, prostaglandin E receptor 2 S homeolog antibody, prostaglandin E receptor 2b (subtype EP2) antibody, PTGER2 antibody, Ptger2 antibody, ptger2a antibody, ptger2.S antibody, ptger2b antibody
    背景
    Prostaglandins (PG's) are produced by the metabolism of arachidonic acid. PGE-2 is one of the five physiologically significant prostanoids known. It's wide spectrum of physiologic and pharmacologic effects in various tissues are mediated through binding to the PGE-2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. PGE-2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo PGE-2-induced internalization. The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue. These receptors are mainly localized in lung and placental tissues and in smooth muscle.Synonyms: EP2, PGE receptor EP2, PGE2 receptor EP2 subtype, Prostaglandin E receptor 2, Prostaglandin E2 receptor EP2, Prostanoid EP2 receptor
    基因ID
    5732
    UniProt
    P43116
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