LEF1 抗体 (Alternate Exon)
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北京 101111
Quick Overview for LEF1 抗体 (Alternate Exon) (ABIN264397)
抗原
See all LEF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Alternate Exon
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特异性
- This antibody recognizes an epitope in amino acids 227-231 of LEF-1. This sequence lies within the context dependent activation domain of LEF-1 and appears to be an alternate splice variant exon of the LEF-1 gene.
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产品特性
- Synonyms: Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha,TCF1-alpha
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纯化方法
- Purified
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免疫原
- Recombinant full-length LEF-1 protein. Genename: LEF1
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亚型
- IgG1
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anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 100-399) antibody
LEF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 331-399) antibodyLEF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 1-399) antibodyLEF1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (Internal Region) antibodyVerified LEF1 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 33-138) antibodyLEF1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1A4B11 unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 14-123) antibodyLEF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5A3 unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 75-216) antibodyLEF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 33-138) antibodyLEF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 10-37), (N-Term) antibodyLEF1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB31989 unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (Internal Region) antibodyLEF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: Detect LEF-1 protein containing the alternately spliced exon between aminoacids 212-241 at 1-5 μg/mL. Positive Control: Cos cells transfected with LEF-1 protein.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.08 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
有效期
- 12 months
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- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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别名
- LEF1
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背景
- Lymphoid Enhancer Factor-1 (LEF-1) is an HMG 1/2-like DNA binding/bending protein and is a member of the LEF/TCF transcription factor family. There are four LEF/TCF family members in mammalian systems (LEF-1, TCF-1, TCF-3 and TCF-4), and orthologs to these factors have been identified in many different species. LEF/TCFs are downstream mediators of Wnt/Wingless signals. Wnt signaling drives cell polarity, cell fate and cell growth decisions in embryonic tissues and in post-natal tissues that continue to develop from mitotically active stem cell precursors. Misregulation of Wnt signaling is also implicated as a root cause of many different cancers, such as colon cancer, melanoma, breast cancer, prostate cancer and others.Synonyms: LEF-1, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha, TCF1-alpha
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基因ID
- 51176
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UniProt
- Q9UJU2
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途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
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