DDR1 抗体 (AA 898-913)
Quick Overview for DDR1 抗体 (AA 898-913) (ABIN2626009)
抗原
See all DDR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 898-913
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特异性
- Detected in T-47D, MDA-MB-175 and HBL-100 breast carcinoma cells, A-431 epidermoid carcinoma cells, SW48 and SNU-C2B colon carcinoma cells and Hs 294T melanoma cells (at protein level). Expressed at low levels in most adult tissues and is highest in the brain, lung, placenta and kidney. Lower levels of expression are detected in melanocytes, heart, liver, skeletal muscle and pancreas. Abundant in breast carcinoma cell lines. In the colonic mucosa, expressed in epithelia but not in the connective tissue of the lamina propria. In the thyroid gland, expressed in the epithelium of the thyroid follicles. In pancreas, expressed in the islets of Langerhans cells, but not in the surrounding epithelial cells of the exocrine pancreas. In kidney, expressed in the epithelia of the distal tubules. Not expressed in connective tissue, endothelial cells, adipose tissue, muscle cells or cells of hematopoietic origin. .
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交叉反应 (详细)
- No cross reactivity with other proteins.
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纯化方法
- Immunogen affinity purified
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MCK10(898-913aa FSQLHRFLAEDALNTV), different from the related rat sequence by one amino acid, and from the related mouse sequence by two amino acids.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Distilled water
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浓度
- Lot specific
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缓冲液
- Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
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- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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别名
- NEP / DDR1
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背景
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Name/Gene ID: DDR1
Subfamily: DDR/TKT
Family: Protein Kinase
Synonyms: DDR1, Cell adhesion kinase, CD167, CD167a antigen, EDDR1, ENTRK4, Mammary carcinoma kinase 10, MCK10, NEP, PTK3, PTK3A, RTK6, Tyrosine-protein kinase CAK, CAK, DDR, Discoidin domain receptor 1, HGK2, MCK-10, NTRK4, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, TRK E, TRKE, Tyrosine kinase DDR -
基因ID
- 780
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途径
- RTK signaling, Smooth Muscle Cell Migration
抗原
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