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Protein Tob1 (TOB1) (pSer164) 抗体

TOB1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2568512
发货至: 中国
  • 抗原 See all Protein Tob1 (TOB1) 抗体
    Protein Tob1 (TOB1)
    抗原表位
    • 15
    • 10
    • 10
    • 9
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer164
    适用
    • 49
    • 31
    • 28
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 63
    • 2
    克隆类型
    • 65
    多克隆
    标记
    • 23
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 32
    • 26
    • 13
    • 13
    • 10
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    The antibody detects endogenous levels of TOB1 only when phosphorylated at serine 164.
    纯化方法
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    免疫原
    TOB1 (phospho Ser164) antibody was raised against a peptide sequence around phosphorylation site of Serine 164 (A-V-S (p)-P-T) derived from Human TOB1.
    亚型
    IgG
    Top Product
    Discover our top product TOB1 Primary Antibody
  • 应用备注
    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store antibody at -20°C for up to one year.
  • 抗原
    Protein Tob1 (TOB1)
    别名
    TOB1 (TOB1 产品)
    别名
    Tob antibody, Trob antibody, APRO5 antibody, APRO6 antibody, PIG49 antibody, TOB antibody, TROB antibody, TROB1 antibody, tob1 antibody, tob1l antibody, wu:fb54d02 antibody, wu:fb98h12 antibody, wu:fd15f10 antibody, zgc:65837 antibody, transducer of ErbB-2.1 antibody, transducer of ERBB2, 1 antibody, transducer of ERBB2, 1a antibody, transducer of ERBB2, 1 S homeolog antibody, transducer of ERBB2, 1b antibody, Tob1 antibody, TOB1 antibody, tob1a antibody, tob1.S antibody, tob1b antibody
    背景
    This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
    分子量
    40 kDa
    基因ID
    10140
    NCBI登录号
    NP_001230806
    UniProt
    P50616
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