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RSK1/2/3/4 (pSer221), (pSer227), (Ser218), (Ser232) 抗体

适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2568448
发货至: 中国
  • 抗原
    RSK1/2/3/4
    抗原表位
    • 9
    • 9
    • 9
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer221, pSer227, Ser218, Ser232
    适用
    人, 小鼠
    宿主
    • 13
    克隆类型
    • 13
    多克隆
    标记
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 6
    • 6
    Western Blotting (WB)
    特异性
    The antibody detects endogenous levels of RSK1/2/3/4 only when phosphorylated at serine 221/227/218/232.
    纯化方法
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    免疫原
    RSK1/2/3/4 (phospho Ser221/227/S218/232) antibody was raised against a peptide sequence around phosphorylation site of Serine 221/227/218/232 (A-Y-S (p)-F-C) derived from Human RSK1/2/3/4.
    亚型
    IgG
  • 应用备注
    Western Blot: 1:500~1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store antibody at -20°C for up to one year.
  • 抗原
    RSK1/2/3/4
    背景
    This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway.
    分子量
    85 kDa
    基因ID
    6195, 6197, 6196
    NCBI登录号
    NP_002944
    UniProt
    Q15418, P51812, Q15349, Q9UK32
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