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FGFR1/FGFR2 抗体 (pTyr463, pTyr466)

适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2568142
发货至: 中国
  • 抗原 See all FGFR1/FGFR2 products
    FGFR1/FGFR2 (FGFR1, FGFR2)
    抗原表位
    • 17
    • 17
    • 8
    • 8
    • 1
    • 1
    • 1
    • 1
    pTyr463, pTyr466
    适用
    • 28
    • 27
    • 12
    人, 小鼠
    宿主
    • 28
    克隆类型
    • 28
    多克隆
    标记
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGFR1/FGFR2 antibody is un-conjugated
    应用范围
    • 21
    • 13
    • 13
    • 8
    • 3
    • 3
    • 1
    Western Blotting (WB)
    特异性
    The antibody detects endogenous levels of FGFR1/2 only when phosphorylated at tyrosine 463/466.
    纯化方法
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    免疫原
    FGFR1/2 (phospho Tyr463/466) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 463/466 (S-E-Y (p)-E-L) derived from Human FGFR1/2.
    亚型
    IgG
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store antibody at -20°C for up to one year.
  • 抗原
    FGFR1/FGFR2 (FGFR1, FGFR2)
    别名
    FGFR1/2 (FGFR1/FGFR2 产品)
    背景
    The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
    分子量
    91 kDa
    基因ID
    2260, 2263
    NCBI登录号
    NP_075598
    UniProt
    P11362, P21802
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