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Cyclin H 抗体 (pThr315)

CCNH 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2568091
发货至: 中国
  • 抗原 See all Cyclin H (CCNH) 抗体
    Cyclin H (CCNH)
    抗原表位
    • 13
    • 12
    • 10
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr315
    适用
    • 89
    • 47
    • 28
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 77
    • 14
    克隆类型
    • 70
    • 21
    多克隆
    标记
    • 51
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Cyclin H antibody is un-conjugated
    应用范围
    • 60
    • 37
    • 23
    • 21
    • 16
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The antibody detects endogenous levels of Cyclin H only when phosphorylated at threonine 315.
    纯化方法
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    免疫原
    Cyclin H (phospho Thr315) antibody was raised against a peptide sequence around phosphorylation site of threonine 315 (E-W-T (p)-D-D) derived from Human Cyclin H .
    亚型
    IgG
    Top Product
    Discover our top product CCNH Primary Antibody
  • 应用备注
    Western Blot: 1:500~1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store antibody at -20°C for up to one year.
  • 抗原
    Cyclin H (CCNH)
    别名
    Cyclin H (CCNH 产品)
    别名
    zgc:114132 antibody, cak antibody, p34 antibody, p37 antibody, Cych antibody, ACYPI004637 antibody, ccnh antibody, Cyclin-H antibody, 142767_at antibody, CG7405 antibody, Dmel\\CG7405 antibody, CAK antibody, 6330408H09Rik antibody, AI661354 antibody, AV102684 antibody, AW538719 antibody, ccnh-A antibody, cyclin H antibody, cyclin-H antibody, Cyclin H antibody, CYclin H antibody, cyclin H L homeolog antibody, CCNH antibody, ccnh antibody, LOC5577539 antibody, Cych antibody, CycH antibody, cyh-1 antibody, Ccnh antibody, ccnh.L antibody
    背景
    Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
    分子量
    36 kDa
    基因ID
    902
    NCBI登录号
    NP_001230
    UniProt
    P51946
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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