FAS 抗体
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北京 101111
Quick Overview for FAS 抗体 (ABIN2568064)
抗原
See all FAS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis.
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纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
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亚型
- IgM kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-buffered aqueous solution, ph7.2.
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储存条件
- 4 °C
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储存方法
- The product should be stored undiluted at 4°C. Do not freeze.
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- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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别名
- CD95
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背景
- The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis. It is expressed on fibroblasts, monocytes, lymphocytes, and neutrophils. CD95 induces apoptosis after binding with CD178 or Fas ligand and the EOS9.1 antibody is reported to be used for inducing apoptosis in Fas-positive cells.
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基因ID
- 355
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UniProt
- P25445
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途径
- p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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