Bloom Syndrome (pThr99) 抗体
适用: 人
IHC, WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原
- Bloom Syndrome
-
抗原表位
- pThr99
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- 非结合性
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 特异性
- The antibody detects endogenous levels of Bloom Syndrome Protein only when phosphorylated at threonine 99.
- 纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 免疫原
- Bloom Syndrome (phospho Thr99) antibody was raised against a peptide sequence around phosphorylation site of threonine 99 (Q-E-T (p)-Q-R) derived from Human Bloom Syndrome.
- 亚型
- IgG
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anti-Bloom Syndrome (AA 65-114), (pThr99) antibody
适用: 人 IHC, ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store antibody at -20°C for up to one year.
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- 抗原
- Bloom Syndrome
- 背景
- Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE).
- 分子量
- 159 kDa
- 基因ID
- 641
- NCBI登录号
- NP_000048
- UniProt
- P54132
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