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SAG 抗体 (pSer412)

SAG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2567047
发货至: 中国
  • 抗原 See all SAG 抗体
    SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))
    抗原表位
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer412
    适用
    • 26
    • 8
    • 7
    • 4
    • 3
    • 1
    宿主
    • 24
    • 6
    • 1
    克隆类型
    • 26
    • 5
    多克隆
    标记
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SAG antibody is un-conjugated
    应用范围
    • 18
    • 13
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    The antibody detects endogenous levels of Arrestin-1 only when phosphorylated at serine 412.
    纯化方法
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    免疫原
    Arrestin 1 (phospho Ser412) antibody was raised against a peptide sequence around phosphorylation site of Serine 412 (T-G-S (p)-P-Q) derived from Human Arrestin 1.
    亚型
    IgG
    Top Product
    Discover our top product SAG Primary Antibody
  • 应用备注
    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store antibody at -20°C for up to one year.
  • 抗原
    SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))
    别名
    Arrestin 1 (SAG 产品)
    别名
    RP47 antibody, S-AG antibody, MGC75721 antibody, MGC84416 antibody, sag antibody, zgc:114197 antibody, SAGMR antibody, SANTI antibody, ARR antibody, sag1 antibody, A930001K18Rik antibody, Arr1 antibody, Irbp antibody, arrestin antibody, S-antigen visual arrestin antibody, S-antigen antibody, S-antigen; retina and pineal gland (arrestin) antibody, S-antigen; retina and pineal gland (arrestin) S homeolog antibody, S-antigen; retina and pineal gland (arrestin) b antibody, S-antigen, retina and pineal gland (arrestin) antibody, S-antigen; retina and pineal gland (arrestin) L homeolog antibody, SAG antibody, PF10_0343 antibody, sag antibody, sag.S antibody, sagb antibody, Sag antibody, sag.L antibody
    背景
    Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein, the binding appears to require additional receptor determinants exposed only in the active receptor conformation.
    分子量
    50 kDa
    基因ID
    408
    NCBI登录号
    NP_004032
    UniProt
    P49407
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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