KCNJ8 抗体 (AA 306-424)
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- 抗原 See all KCNJ8 抗体
- KCNJ8 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8))
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抗原表位
- AA 306-424
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KCNJ8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects ~45 kDa.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Fusion protein amino acids 306-424 (Cytoplasmic C-terminus) of rat Kir6.1
- 克隆位点
- S366-60
- 亚型
- IgG2a
- Top Product
- Discover our top product KCNJ8 Primary Antibody
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- 应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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A 1:100 dilution of ABIN2485699 was sufficient for detection of Kir6.1 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- KCNJ8 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8))
- 别名
- Kir6.1 (KCNJ8 产品)
- 别名
- kir6.1 antibody, KIR6.1 antibody, uKATP-1 antibody, AI448900 antibody, Kir6.1 antibody, gnite antibody, slmbr antibody, sltr antibody, UKATP1 antibody, si:dkey-183c2.2 antibody, zkir6.1 antibody, potassium voltage-gated channel subfamily J member 8 antibody, potassium channel, inwardly rectifying subfamily J, member 8 antibody, potassium inwardly-rectifying channel, subfamily J, member 8 antibody, potassium channel, inwardly rectifying subfamily J, member 8 S homeolog antibody, KCNJ8 antibody, kcnj8 antibody, Kcnj8 antibody, kcnj8.S antibody
- 背景
- Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family (1-3). This is predominantly detected in fetal and adult hearts, and defects can be associated with J-wave syndromes, a group of heart disorders characterized by early repolarization events (4).
- 基因ID
- 25472
- NCBI登录号
- NP_058795
- UniProt
- Q63664
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