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SCN3B 抗体 (AA 1-215) (PerCP)

SCN3B 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S396-29 PerCP
产品编号 ABIN2485590
发货至: 中国
  • 抗原 See all SCN3B 抗体
    SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))
    抗原表位
    • 15
    • 10
    • 1
    • 1
    • 1
    • 1
    AA 1-215
    适用
    • 32
    • 13
    • 9
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    大鼠
    宿主
    • 27
    • 10
    小鼠
    克隆类型
    • 28
    • 9
    单克隆
    标记
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCN3B antibody is conjugated to PerCP
    应用范围
    • 35
    • 13
    • 13
    • 9
    • 9
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    Detects ~40 kDa. Does not cross-reat with NavBeta1, Navbeta2, or Navbeta4.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Protein G Purified
    免疫原
    Fusion protein amino acids 1-215 (full-length) of rat NavBeta3
    克隆位点
    S396-29
    亚型
    IgG2b
    Top Product
    Discover our top product SCN3B Primary Antibody
  • 应用备注
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    A 1:100 dilution of ABIN2485590 was sufficient for detection of NavBeta3 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))
    别名
    NaVbeta3 (SCN3B 产品)
    别名
    1110001K16Rik antibody, 4833414B02Rik antibody, Scnb3 antibody, HSA243396 antibody, SCNB3 antibody, sodium voltage-gated channel beta subunit 3 antibody, sodium channel, voltage-gated, type III, beta antibody, SCN3B antibody, Scn3b antibody
    背景
    Nav Beta 3 (SCN3B) belongs to the voltage-gated sodium channel group, and modulates channel gating kinetics. It inactivates the sodium channel opening more slowly than its Beta1 subunit. It is also unique in causing persistent sodium currents which are thought to amplify summation of synaptic imputs which is likely to increase the excitability of specific neurons to their individual inputs (2). Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (1, 2). Defects in SCN3B are the cause of Brugada syndrome (3).
    基因ID
    245956
    NCBI登录号
    NP_620797
    UniProt
    Q9JK00
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