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PARP1 抗体

PARP1 适用: 人, 小鼠, 大鼠, Drosophila melanogaster, Hamster, 非洲爪蟾 WB, ELISA, IP, IF, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal A6-4-12 unconjugated
产品编号 ABIN2476185
发货至: 中国
  • 抗原 See all PARP1 抗体
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    适用
    • 217
    • 55
    • 42
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Drosophila melanogaster, Hamster, 非洲爪蟾
    宿主
    • 213
    • 21
    • 1
    小鼠
    克隆类型
    • 206
    • 29
    单克隆
    标记
    • 133
    • 16
    • 15
    • 13
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PARP1 antibody is un-conjugated
    应用范围
    • 146
    • 117
    • 69
    • 32
    • 31
    • 25
    • 24
    • 22
    • 20
    • 17
    • 16
    • 7
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    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    Fruit Fly (Drosophila melanogaster), Hamster, 小鼠, 大鼠, 非洲爪蟾
    产品特性
    Purified IgG
    纯化方法
    Purified
    克隆位点
    A6-4-12
    亚型
    IgG1
    Top Product
    Discover our top product PARP1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
  • Pinton, Manente, Murer, De Marino, Mutti, Moro: "PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1." in: Journal of cellular and molecular medicine, Vol. 17, Issue 2, pp. 233-41, (2013) (PubMed).

    Harris, Jakob, Taucher-Scholz, Dianov, Becherel, Lavin: "Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage." in: Human molecular genetics, Vol. 18, Issue 21, pp. 4102-17, (2009) (PubMed).

    Freire, dAdda Di Fagagna, Wu, Pedrazzi, Stagljar, Hickson, Jackson: "Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha." in: Nucleic acids research, Vol. 29, Issue 15, pp. 3172-80, (2001) (PubMed).

  • 抗原
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    别名
    POLY(ADP-RIBOSE) POLYMERASE-1 (PARP1 产品)
    基因ID
    142
    UniProt
    P09874
    途径
    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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