FAS 抗体
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北京 101111
Quick Overview for FAS 抗体 (ABIN2470748)
抗原
See all FAS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Ion Exchange Chromatography
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免疫原
- FAS monoclonal antibody was raised against HUT - 78 human T cell lymphoma cell line (Human).
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亚型
- IgG1
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应用备注
- FAS antibody can be used in Western Blot at 1 - 2 μg/mL, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation starting at 300 - 500 g/1E6 cells.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 20 mM Tris/HCl, 15 mM sodium azide, approx., pH 7.4.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store FAS antibody at 4 °C or -20 °C.
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- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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别名
- FAS
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背景
- Reacts with CD95 (Fas/APO-1), a 46 kDa single chain type I glycoprotein of the tumour necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells. It seems that the antibody LT95 does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule.
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基因ID
- 355
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UniProt
- P25445
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途径
- p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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