TLR8 抗体 (AA 750-850)
Quick Overview for TLR8 抗体 (AA 750-850) (ABIN2470503)
抗原
See all TLR8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 750-850
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纯化方法
- Protein G Column
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免疫原
- TLR8 monoclonal antibody was raised against amino acids 750 - 850 of TLR8 (Human).
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亚型
- IgG kappa
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anti-Toll-Like Receptor 8 (TLR8) (AA 849-1041) antibody
TLR8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (AA 723-825) antibodyTLR8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C6 unconjugated
anti-Toll-Like Receptor 8 (TLR8) (C-Term) antibodyTLR8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (AA 844-1039) antibodyTLR8 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (AA 844-1039) antibodyTLR8 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Toll-Like Receptor 8 (TLR8) (AA 750-850) antibody (PE)TLR8 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal 44C143 PE
anti-Toll-Like Receptor 8 (TLR8) (AA 957-987) antibodyTLR8 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (AA 434-463) antibodyTLR8 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (Middle Region) antibodyTLR8 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (C-Term) antibodyTLR8 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 山羊, 豚鼠, 马, 绵羊, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- TLR8 antibody can be used in immunohistochemistry starting at 1:100, and flow cytometry.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.2 mLPBS, 0.05 % BSA, 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store TLR8 antibody at 4 °C or -20 °C.
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- TLR8 (Toll-Like Receptor 8 (TLR8))
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别名
- TLR8
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背景
- Ten human homologs of TLRs (TLR1-10) have been described. TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120 kDa (4,5). Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
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基因ID
- 51311
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UniProt
- Q9NR97
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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