HSP90B2P 抗体 (AA 289-300)
HSP90B2P
适用: 人, 小鼠, 大鼠, 小鸡, Drosophila melanogaster, 猴
ELISA, WB, IHC
宿主: 兔
Polyclonal
unconjugated
1 image
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- 抗原 See all HSP90B2P products
- HSP90B2P (Heat Shock Protein 90kDa beta (Grp94), Member 2, Pseudogene (HSP90B2P))
- 抗原表位
- AA 289-300
- 适用
- 人, 小鼠, 大鼠, 小鸡, Drosophila melanogaster, 猴
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSP90B2P antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Immunoaffinity Chromatography
- 免疫原
- HSP90B2P antibody was raised against amino acids 289-300 of HSP90B2P (Human).
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- 应用备注
- HSP90B2P antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 - 10 μg/mL, immunoprecipitation, and flow cytometry.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies avoid freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store HSP90B2P antibody at 4 °C or -20 °C.
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- 抗原
- HSP90B2P (Heat Shock Protein 90kDa beta (Grp94), Member 2, Pseudogene (HSP90B2P))
- 别名
- HSP90B2P (HSP90B2P 产品)
- 别名
- GRP94P1 antibody, GRP94b antibody, HSP antibody, HSPCP2 antibody, TRA1P1 antibody, TRAP1 antibody, heat shock protein 90 beta family member 2, pseudogene antibody, HSP90B2P antibody
- 背景
- Hsp90 is a member of the heat shock protein 90 family that functions as a molecular chaperone and has ATPase activity. Hsp90 family proteins are highly conserved between isoforms and species. Several signal transduction pathways depend on Hsp90 function including erbB2, steroid hormone receptors (such as androgen, progesterone, glucocorticoid, and aryl-hydrocarbon), and hypoxia sensing (Hif1alpha). Recent reports show that tumor cells are more sensitive to Hsp90 inhibition and that Hsp90 from tumor cells is more sensitive to small molecule inhibitors (eg 17AAG). The mechanism of this differential sensitivity of normal versus tumor Hsp90 is not known (although mutation has been ruled out). One possible mechanism may be differences in post-translational modification of tumor Hsp90. Hsp90 is a cytoplasmic protein that forms a homodimer in vivo, and interacts with TOM34, AHSA1, HDAC6 and SMYD3.
- 基因ID
- 3320
- UniProt
- P07900
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