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GPR37 抗体 (N-Term)
GPR37
适用: 人, Gorilla, Gibbon
ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
GPR37抗体详情
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抗原
See all GPR37 抗体
GPR37
(G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))
抗原表位
All epitopes for GPR37 抗体
N-Term
适用
All reactivities for GPR37 抗体
人, Gorilla, Gibbon
宿主
All hosts for GPR37 抗体
兔
克隆类型
All clonalities for GPR37 抗体
多克隆
标记
All conjugates for GPR37 抗体
This GPR37 antibody is un-conjugated
应用范围
All applications for GPR37 抗体
ELISA, Immunohistochemistry (IHC)
特异性
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
纯化方法
Immunoaffinity Chromatography
免疫原
PAEL Receptor antibody was raised against a peptide located in the N-Terminal extracellular domain of PAEL Receptor (Human).
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Discover our top product GPR37 Primary Antibody
Alternatives
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使用细节
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应用备注
PAEL Receptor antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS, 0.1 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
As with all antibodies avoid freeze/thaw cycles.
储存条件
4 °C/-80 °C
储存方法
PAEL Receptor antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
GPR37目标详情
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抗原
GPR37
(G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))
Abstract
GPR37 产品
别名
ACCA antibody, EDNRBL antibody, PAELR antibody, hET(B)R-LP antibody, AI848630 antibody, Pael-R antibody, Ednrbl antibody, G protein-coupled receptor 3 antibody, G protein-coupled receptor 37 antibody, GPR3 antibody, GPR37 antibody, Gpr37 antibody
背景
GPR37 is an Orphan-A GPCR with an unknown ligand. GPR37 was recently identified as the PAEL receptor, a Parkin substrate involved in autosomal recessive juvenile Parkinson's (PDJ) disease. The PAEL receptor becomes unfolded, insoluble, and ubiquitinated when overexpressed, leading to unfolded protein-induced cell death. When the PAEL receptor is ubiquitinated by Parkin, it gets degraded, resulting in the suppression of cell death. The insoluble form of the PAEL receptor accumulates in the brains of PDJ patients and may cause selective neuronal death.
基因ID
2861
UniProt
O15354
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