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GPR37 抗体 (N-Term)

GPR37 适用: 人, Gorilla, Gibbon ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2469255
发货至: 中国
  • 抗原 See all GPR37 抗体
    GPR37 (G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))
    抗原表位
    • 15
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term
    适用
    • 46
    • 28
    • 15
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, Gorilla, Gibbon
    宿主
    • 45
    • 1
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPR37 antibody is un-conjugated
    应用范围
    • 17
    • 14
    • 13
    • 13
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    特异性
    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    PAEL Receptor antibody was raised against a peptide located in the N-Terminal extracellular domain of PAEL Receptor (Human).
    Top Product
    Discover our top product GPR37 Primary Antibody
  • 应用备注
    PAEL Receptor antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, 0.1 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies avoid freeze/thaw cycles.
    储存条件
    4 °C/-80 °C
    储存方法
    PAEL Receptor antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
  • 抗原
    GPR37 (G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))
    Abstract
    GPR37 产品
    别名
    ACCA antibody, EDNRBL antibody, PAELR antibody, hET(B)R-LP antibody, AI848630 antibody, Pael-R antibody, Ednrbl antibody, G protein-coupled receptor 3 antibody, G protein-coupled receptor 37 antibody, GPR3 antibody, GPR37 antibody, Gpr37 antibody
    背景
    GPR37 is an Orphan-A GPCR with an unknown ligand. GPR37 was recently identified as the PAEL receptor, a Parkin substrate involved in autosomal recessive juvenile Parkinson's (PDJ) disease. The PAEL receptor becomes unfolded, insoluble, and ubiquitinated when overexpressed, leading to unfolded protein-induced cell death. When the PAEL receptor is ubiquitinated by Parkin, it gets degraded, resulting in the suppression of cell death. The insoluble form of the PAEL receptor accumulates in the brains of PDJ patients and may cause selective neuronal death.
    基因ID
    2861
    UniProt
    O15354
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