DDR2 抗体 (truncated)
Quick Overview for DDR2 抗体 (truncated) (ABIN2464044)
抗原
See all DDR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- truncated
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免疫原
- Ni-NTA purified truncated recombinant DDR2-Trx expressed in E. Coli strain BL21 (DE3).
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亚型
- IgG2a
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anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibody
DDR2 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3B11E4 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyDDR2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 245-350) antibodyDDR2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 447-540) antibodyDDR2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 578-817) antibodyDDR2 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (C-Term) antibodyKO Validated DDR2 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyDDR2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB17713 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 31-80) antibodyDDR2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 816-843) antibodyDDR2 适用: 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyDDR2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- -20 °C
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储存方法
- DDR2 monoclonal antibody can be stored at -20 °C, stable for one year.
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- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
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别名
- DDR2
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背景
- DDR2 (discoidin domain receptor family, member 2) is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/ threonine (STK) kinase catalytic domains. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
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基因ID
- 4921
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UniProt
- Q16832
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途径
- RTK signaling
抗原
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