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NLRC4 抗体

NLRC4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2463643
发货至: 中国
  • 抗原 See all NLRC4 抗体
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    适用
    • 39
    • 15
    • 6
    • 2
    宿主
    • 28
    • 9
    • 2
    克隆类型
    • 29
    • 10
    多克隆
    标记
    • 23
    • 2
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    • 2
    • 2
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    This NLRC4 antibody is un-conjugated
    应用范围
    • 28
    • 17
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CARD12.
    Top Product
    Discover our top product NLRC4 Primary Antibody
  • 应用备注
    CARD12 antibody can be used for detection of CARD12 by ELISA at 1:62500. CARD12 antibody can be used for detection of CARD12 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store CARD12 antibody at -20 °C.
  • 抗原
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    别名
    CARD12 (NLRC4 产品)
    别名
    CARD12 antibody, CLAN antibody, CLAN1 antibody, CLANA antibody, CLANB antibody, CLANC antibody, CLAND antibody, CLR2.1 antibody, IPAF antibody, 9530011P19Rik antibody, Card12 antibody, NLR family CARD domain containing 4 antibody, NLR family, CARD domain containing 4 antibody, NLRC4 antibody, Nlrc4 antibody
    背景
    In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1, NOD1, and NOD2. These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.
    分子量
    116 kDa
    基因ID
    58484
    NCBI登录号
    NP_067032
    UniProt
    Q9NPP4
    途径
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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