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NOX1 抗体

NOX1 适用: 人, 犬 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2463016
发货至: 中国
  • 抗原 See all NOX1 抗体
    NOX1 (NADPH Oxidase 1 (NOX1))
    适用
    • 41
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 犬
    宿主
    • 41
    • 2
    • 1
    克隆类型
    • 43
    • 2
    多克隆
    标记
    • 29
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOX1 antibody is un-conjugated
    应用范围
    • 33
    • 21
    • 10
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NOX1.
    Top Product
    Discover our top product NOX1 Primary Antibody
  • 应用备注
    NOX1 antibody can be used for detection of NOX1 by ELISA at 1:62500. NOX1 antibody can be used for detection of NOX1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store NOX1 antibody at -20 °C.
  • 抗原
    NOX1 (NADPH Oxidase 1 (NOX1))
    别名
    NOX1 (NOX1 产品)
    背景
    Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. The NOH-1S currents were reversibly blocked by zinc, a known H+ channel inhibitor. The NOH-1S variant does not contain an electron transport chain and it is thought that H+ conductance is its main physiologic function, whereas NOH-1L may conduct H+ ions as part of its electron transport mechanism.
    分子量
    65 kDa, 59 kDa
    基因ID
    27035
    NCBI登录号
    NP_008983
    UniProt
    Q9Y5S8
    途径
    Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport
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