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NOX1 抗体

This anti-NOX1 antibody is a 兔 多克隆 antibody detecting NOX1 in WB 和 ELISA. Suitable for 人 和 犬.
产品编号 ABIN2463016
发货至: 中国

Quick Overview for NOX1 抗体 (ABIN2463016)

抗原

See all NOX1 抗体
NOX1 (NADPH Oxidase 1 (NOX1))

适用

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人, 犬

宿主

  • 44
  • 4
  • 1

克隆类型

  • 46
  • 4
多克隆

标记

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This NOX1 antibody is un-conjugated

应用范围

  • 37
  • 22
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  • 8
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  • 6
  • 2
  • 1
  • 1
  • 1
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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NOX1.
  • 应用备注

    NOX1 antibody can be used for detection of NOX1 by ELISA at 1:62500. NOX1 antibody can be used for detection of NOX1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store NOX1 antibody at -20 °C.
  • 抗原

    NOX1 (NADPH Oxidase 1 (NOX1))

    别名

    NOX1

    背景

    Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. The NOH-1S currents were reversibly blocked by zinc, a known H+ channel inhibitor. The NOH-1S variant does not contain an electron transport chain and it is thought that H+ conductance is its main physiologic function, whereas NOH-1L may conduct H+ ions as part of its electron transport mechanism.

    分子量

    65 kDa, 59 kDa

    基因ID

    27035

    NCBI登录号

    NP_008983

    UniProt

    Q9Y5S8

    途径

    Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport
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