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EBP 抗体

EBP 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2463004
发货至: 中国
  • 抗原 See all EBP 抗体
    EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))
    适用
    • 41
    • 13
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 42
    克隆类型
    • 42
    多克隆
    标记
    • 16
    • 6
    • 6
    • 6
    • 4
    • 4
    This EBP antibody is un-conjugated
    应用范围
    • 34
    • 33
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EBP.
    Top Product
    Discover our top product EBP Primary Antibody
  • 应用备注
    EBP antibody can be used for detection of EBP by ELISA at 1:12500. EBP antibody can be used for detection of EBP by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store EBP antibody at -20 °C.
  • 抗原
    EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))
    别名
    EBP (EBP 产品)
    别名
    cdpx2 antibody, cho2 antibody, cpx antibody, cpxd antibody, zgc:91895 antibody, CDPX2 antibody, CHO2 antibody, CPX antibody, CPXD antibody, AI255399 antibody, Pabp antibody, Td antibody, mSI antibody, emopamil binding protein (sterol isomerase) antibody, emopamil binding protein (sterol isomerase) L homeolog antibody, phenylalkylamine Ca2+ antagonist (emopamil) binding protein antibody, Ebp antibody, ebp.L antibody, ebp antibody, EBP antibody
    背景
    EBP is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in EBP gene cause Chondrodysplasia punctata 2 (CDPX2, also known as Conradi-Hunermann syndrome).Emopamil-binding protein (EBP) is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. EBP shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of EBP is its high content of aromatic amino acid residues (>23 % ) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2, also known as Conradi-Hunermann syndrome).
    分子量
    26 kDa
    基因ID
    10682
    NCBI登录号
    NP_006570
    UniProt
    Q15125
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