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TAPBP 抗体

TAPBP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2462853
发货至: 中国
  • 抗原 See all TAPBP 抗体
    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
    适用
    • 37
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    • 5
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    • 1
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    • 1
    宿主
    • 37
    克隆类型
    • 37
    多克隆
    标记
    • 20
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    • 2
    • 2
    • 2
    • 2
    • 1
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    This TAPBP antibody is un-conjugated
    应用范围
    • 30
    • 14
    • 9
    • 3
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    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TAPBP.
    Top Product
    Discover our top product TAPBP Primary Antibody
  • 应用备注
    TAPBP antibody can be used for detection of TAPBP by ELISA at 1:12500. TAPBP antibody can be used for detection of TAPBP by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store TAPBP antibody at -20 °C.
  • 抗原
    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
    别名
    TAPBP (TAPBP 产品)
    别名
    SI:dZ179B20.1 antibody, SI:dZ179B20.3 antibody, SI:dZ179B20.7 antibody, mhc1uda antibody, mhc1ufa antibody, tpsn antibody, zgc:109814 antibody, tapbp antibody, TAPBP antibody, D17Wsu91e antibody, TPN antibody, NGS17 antibody, TAPA antibody, TPSN antibody, TAP binding protein (tapasin), tandem duplicate 1 antibody, TAP binding protein antibody, tapbp.1 antibody, tapbp antibody, TAPBP antibody, Tapbp antibody
    背景
    TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
    分子量
    46 kDa, 44 kDa
    基因ID
    6892
    NCBI登录号
    NP_003181
    UniProt
    O15533
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