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PTPRR 抗体

PTPRR 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2462848
发货至: 中国
  • 抗原 See all PTPRR 抗体
    PTPRR (Protein tyrosine Phosphatase, Receptor Type, R (PTPRR))
    适用
    • 51
    • 14
    • 11
    • 9
    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 49
    • 3
    克隆类型
    • 50
    • 2
    多克隆
    标记
    • 24
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTPRR antibody is un-conjugated
    应用范围
    • 48
    • 16
    • 13
    • 13
    • 11
    • 8
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PTPRR.
    Top Product
    Discover our top product PTPRR Primary Antibody
  • 应用备注
    PTPRR antibody can be used for detection of PTPRR by ELISA at 1:62500. PTPRR antibody can be used for detection of PTPRR by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PTPRR antibody at -20 °C.
  • 抗原
    PTPRR (Protein tyrosine Phosphatase, Receptor Type, R (PTPRR))
    别名
    PTPRR (PTPRR 产品)
    别名
    EC-PTP antibody, PCPTP1 antibody, PTP-SL antibody, PTPBR7 antibody, PTPRQ antibody, Pcptp1 antibody, ec-ptp antibody, pcptp1 antibody, ptp-sl antibody, ptpbr7 antibody, PTPRR antibody, Gmcp1 antibody, RPTPRR antibody, mPTP213 antibody, protein tyrosine phosphatase, receptor type R antibody, protein tyrosine phosphatase, receptor type, R antibody, protein tyrosine phosphatase, receptor type R L homeolog antibody, protein tyrosine phosphatase, receptor type, r antibody, receptor-type tyrosine-protein phosphatase R antibody, PTPRR antibody, Ptprr antibody, ptprr.L antibody, ptprr antibody, LOC100715069 antibody
    背景
    PTPRR is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation. Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component, encoded by this gene, that serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Mutations in this gene cause autosomal dominant dyskeratosis congenita, and may also be associated with some cases of aplastic anemia.
    分子量
    46 kDa, 74 kDa
    基因ID
    5801
    NCBI登录号
    NP_570897
    UniProt
    Q7Z2V8
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