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- 抗原 See all UBE2L3 抗体
- UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBE2L3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 纯化方法
- Antibody is purified by protein A chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBE2L3.
- Top Product
- Discover our top product UBE2L3 Primary Antibody
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anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (AA 73-212) antibody
UBE2L3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (AA 4-154) antibodyUBE2L3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) antibodyUBE2L3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (C-Term) antibodyVerified UBE2L3 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (C-Term) antibodyUBE2L3 适用: 人 WB, IHC (p), IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (AA 1-154) antibodyUBE2L3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (AA 1-154) antibodyUBE2L3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B7 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (C-Term) antibodyUBE2L3 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (C-Term) antibodyUBE2L3 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 小鸡, 非洲爪蟾, 斑马鱼, Pig, Bat, 猴, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (AA 35-84) antibodyUBE2L3 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 小鸡, 非洲爪蟾, 斑马鱼, Pig, Bat, 猴, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- UBE2L3 antibody can be used for detection of UBE2L3 by ELISA at 1:312500. UBE2L3 antibody can be used for detection of UBE2L3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store UBE2L3 antibody at -20 °C.
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- 抗原
- UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))
- 别名
- UBE2L3 (UBE2L3 产品)
- 别名
- E2-F1 antibody, L-UBC antibody, UBCH7 antibody, UbcM4 antibody, C79827 antibody, Ubce7 antibody, ube2l3 antibody, wu:fc22h11 antibody, zgc:86727 antibody, UBE2L3 antibody, ube2l3l antibody, wu:fb38h03 antibody, ubiquitin conjugating enzyme E2 L3 antibody, ubiquitin-conjugating enzyme E2L 3 antibody, ubiquitin-conjugating enzyme E2L 3a antibody, ubiquitin conjugating enzyme E2 L3 S homeolog antibody, ubiquitin-conjugating enzyme E2L 3b antibody, UBE2L3 antibody, Ube2l3 antibody, ube2l3a antibody, ube2l3.S antibody, ube2l3b antibody
- 背景
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
- 分子量
- 75 kDa, 75 kDa
- 基因ID
- 7332
- NCBI登录号
- NP_003338
- UniProt
- P68036
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