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C-Type Lectin Domain Family 4, Member M (CLEC4M) 抗体

CLEC4M 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2462578
发货至: 中国
  • 抗原 See all C-Type Lectin Domain Family 4, Member M (CLEC4M) 抗体
    C-Type Lectin Domain Family 4, Member M (CLEC4M)
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    非结合性
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Antibody is purified by protein A chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLEC4M.
    Top Product
    Discover our top product CLEC4M Primary Antibody
  • 应用备注
    CLEC4M antibody can be used for detection of CLEC4M by ELISA at 1:312500. CLEC4M antibody can be used for detection of CLEC4M by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store CLEC4M antibody at -20 °C.
  • 抗原
    C-Type Lectin Domain Family 4, Member M (CLEC4M)
    别名
    CLEC4M (CLEC4M 产品)
    别名
    CD209L antibody, CD299 antibody, DC-SIGN2 antibody, DC-SIGNR antibody, DCSIGNR antibody, HP10347 antibody, L-SIGN antibody, LSIGN antibody, CD209B antibody, C-type lectin domain family 4 member M antibody, CLEC4M antibody
    背景
    CLEC4M is a type II integral membrane protein that is 77 % identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77 % identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
    分子量
    44 kDa, 45 kDa, 43 kDa, 30 kDa, 30 kDa, 28 kDa
    基因ID
    10332
    NCBI登录号
    NP_055072
    UniProt
    Q9H2X3
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