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LKB1 抗体

This anti-LKB1 antibody is a 兔 多克隆 antibody detecting LKB1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠, 大鼠, 斑马鱼 和 犬.
产品编号 ABIN2462468
发货至: 中国

Quick Overview for LKB1 抗体 (ABIN2462468)

抗原

See all LKB1 (STK11) 抗体
LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

适用

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人, 小鼠, 大鼠, 斑马鱼, 犬

宿主

  • 161
  • 11

克隆类型

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  • 9
多克隆

标记

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This LKB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STK11.
  • 应用备注

    STK11 antibody can be used for detection of STK11 by ELISA at 1:1562500. STK11 antibody can be used for detection of STK11 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store STK11 antibody at -20 °C.
  • 抗原

    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

    别名

    STK11

    背景

    STK11is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in its gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

    分子量

    48 kDa

    基因ID

    6794

    NCBI登录号

    NP_000446

    UniProt

    Q15831

    途径

    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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