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- 抗原 See all CYP2D6 抗体
- CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP2D6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Antibody is purified by protein A chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CYP2D6.
- Top Product
- Discover our top product CYP2D6 Primary Antibody
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anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 236-472) antibody
CYP2D6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 315-347), (C-Term) antibodyCYP2D6 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) antibodyCYP2D6 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 268-457) antibodyCYP2D6 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 315-347) antibodyCYP2D6 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) antibodyCYP2D6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 91-190) antibodyCYP2D6 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 1-497) antibodyCYP2D6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 101-150) antibodyCYP2D6 适用: 人, 猴, 绵羊, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 20-230) antibodyCYP2D6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- CYP2D6 antibody can be used for detection of CYP2D6 by ELISA at 1:312500. CYP2D6 antibody can be used for detection of CYP2D6 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store CYP2D6 antibody at -20 °C.
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- 抗原
- CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
- 别名
- CYP2D6 (CYP2D6 产品)
- 别名
- CPD6 antibody, CYP2D antibody, CYP2D7AP antibody, CYP2D7BP antibody, CYP2D7P2 antibody, CYP2D8P2 antibody, CYP2DL1 antibody, CYPIID6 antibody, P450-DB1 antibody, P450C2D antibody, P450DB1 antibody, CYP2D42 antibody, MGC64445 antibody, cyp2d2 antibody, cyp2d6-a antibody, CYP2D6 antibody, cytochrome P450 family 2 subfamily D member 6 antibody, cytochrome P450, family 2, subfamily D, polypeptide 6 antibody, cytochrome 2D6 antibody, cytochrome P450 family 2 subfamily D member 6 S homeolog antibody, cytochrome P450 2D6 antibody, cytochrome P450 2D6-like antibody, CYP2D6 antibody, cyp2d6-b antibody, cyp2d6.S antibody, cyp2d6 antibody, LOC100988273 antibody
- 背景
- CYP2D6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20 % of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug, sparteine and propafenone, both anti-arrythmic drugs, and amitryptiline, an anti-depressant.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20 % of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug, sparteine and propafenone, both anti-arrythmic drugs, and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population, certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 55 kDa
- 基因ID
- 1565
- NCBI登录号
- NP_000097
- UniProt
- P10635
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