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TARDBP 抗体

This anti-TARDBP antibody is a 兔 多克隆 antibody detecting TARDBP in WB, IHC 和 ELISA. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN2461819
发货至: 中国

Quick Overview for TARDBP 抗体 (ABIN2461819)

抗原

See all TARDBP 抗体
TARDBP (TAR DNA Binding Protein (TARDBP))

适用

  • 90
  • 52
  • 46
  • 12
  • 7
  • 7
  • 7
  • 6
  • 6
  • 5
  • 4
  • 4
  • 3
  • 1
人, 小鼠, 大鼠, 犬

宿主

  • 90
  • 22
  • 1

克隆类型

  • 76
  • 37
多克隆

标记

  • 75
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TARDBP antibody is un-conjugated

应用范围

  • 92
  • 50
  • 38
  • 35
  • 27
  • 19
  • 15
  • 15
  • 13
  • 13
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TARDBP.
  • 应用备注

    TARDBP antibody can be used for detection of TARDBP by ELISA at 1:1562500. TARDBP antibody can be used for detection of TARDBP by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store TARDBP antibody at -20 °C.
  • 抗原

    TARDBP (TAR DNA Binding Protein (TARDBP))

    别名

    TARDBP

    背景

    HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

    分子量

    45 kDa

    基因ID

    23435

    NCBI登录号

    NP_031401

    UniProt

    Q13148

    途径

    Positive Regulation of Peptide Hormone Secretion
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